{Hero total 3-bet range}
={value hands and 5-bet bluff hands} + {3-bet bluff hands}
={QQ+, AK, A5s, A4s}
+ 40% x {A9s-A6s,ATo-A8o,K9s-K6s,KJo-K9o,Q9s-Q6s,QJo-Q9o}
Even against a TAG CO raiser with a solid ~25% opening range, you can 3-bet almost 8% on the button and there isn’t anything he can do to exploit your loose 3-bets. And if he defends poorly, for example by not 4-bet-bluffing enough, or not being willing to use JJ/AQ as value hands, you can deviate from optimal play and attack him even harder. The first adjustment against a weak/passive CO raiser who folds a lot to 3-bets is to increase your fixed 3-bet bluff percentage for the candidate list. You might increase the bluff candidate 3-betting frequency from 40% to 60%. If Villain (and the blinds) doesn’t adjust to your exploitative, loose 3-betting, you’ll be printing money.